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Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy

Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy

Recruiting
18 years and older
All
Phase N/A
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  • Simplified (AI rewritten)

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Overview

Deep brain stimulation (DBS) is used to treat epilepsy in cases where patients are medically refractory and are not candidates for surgical resection. This therapy has been shown to be effective in seizure reduction, yet very few patients achieve the ultimate goal of seizure freedom. Implantable neural stimulators (INSs) have many parameters that may be adjusted, and could be tuned to achieve very patient specific therapies. This study will develop a platform for stimulation setting optimization based on power spectral density (PSD) measures.

Eligibility

Inclusion Criteria:

  • medically refractory epilepsy
  • already have a deep brain stimulator in place

Exclusion Criteria:

  • severe dementia at investigator discretion

Study details
    Refractory Epilepsy
    Deep Brain Stimulation

NCT05493722

University of Minnesota

1 November 2025

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