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A Post-market Clinical Follow up of the Genio™ System for the Treatment of Obstructive Sleep Apnea in Adults

Recruiting
18 years of age
Both
Phase N/A

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Overview

The primary objective of this study is to confirm the safety and clinical effectiveness of the Genio™ system, used according to its instructions for use, in moderate to severe Obstructive Sleep Apnea (OSA) adult patients over a period of 3 years post-surgery.

Description

This study is a multicenter, prospective single arm PMCF. Following activation of the Genio™ system between 6 to 10 weeks post-surgery, patients will be followed at 3 months, 6 months, 9 months, 12 months and then every year for a total period of 5 years after surgery. Phone calls follow-up will be performed at Month 18, Month 30, Month 42 and Month 54.

Eligibility

Inclusion Criteria:

  • Body Mass Index (BMI) < 35 kg/m2
  • AHI between 15 to 65 events/hour documented by a PSG during the screening phase.
  • Has either not tolerated, has failed or refused Positive Airway Pressure (PAP) or Mandibular Advancement Device (MAD) treatments.

Exclusion Criteria:

  • Night shift worker
  • Significant comorbidities that contraindicates surgery
  • Life expectancy < 12 months
  • Participation in another clinical study (excluding registries) during the study period (3 years).

Study details

Obstructive Sleep Apnea

NCT04031040

Nyxoah S.A.

26 January 2024

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