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Assessing the Accuracy of Seismofit® as an Estimate of VO2 Peak in Patients With Hepato-pancreato-biliary, Colorectal, and Gastro-oesophageal Cancer

Assessing the Accuracy of Seismofit® as an Estimate of VO2 Peak in Patients With Hepato-pancreato-biliary, Colorectal, and Gastro-oesophageal Cancer

Non Recruiting
18 years and older
All
Phase N/A

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Overview

Our study aims to assess the relationship between the Seismofit® derived VO2 peak estimate and CPET-measured VO2 peak in patients who are having CPET as part of their preoperative workup. Our aim is to establish whether Seismofit® can be considered a cheaper, less resource intensive and better tolerated alternative to the CPET, or whether it might be useful as a screening tool to efficiently identify patients with exercise intolerance who may benefit from further characterisation by CPET.

Eligibility

Inclusion Criteria:

  1. Age ≥18
  2. Scheduled for elective surgery for resection of HPB, colorectal or gastro-oesophageal primary or secondary cancer
  3. Undergoing CPET as part of routine pre-operative investigations

Exclusion Criteria:

  1. Subjects unable to give voluntary written informed consent to participate in this study
  2. Diagnosis of moderate or worse stenosis or regurgitation of any cardiac valve
  3. Previous aortic or mitral valve surgery, valvuloplasty or transcatheter valve implantation
  4. Permanent pacemaker or cardiac resynchronisation device in situ
  5. Diagnosis of severe pulmonary hypertension
  6. Permanent atrial fibrillation

Study details
    Hepato-Biliary Carcinoma in Situ Nos
    Pancreatic Cancer
    Colorectal Cancer
    Gastric Cancer
    Oesophageal Cancer

NCT05831488

Royal Marsden NHS Foundation Trust

20 August 2025

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