Overview
The primary goals of this study are to use optical coherence tomography (OCT) angiography (blood vessel mapping) to:
- diagnose the presence of new blood vessels in wet age-related macular degeneration (AMD)
- evaluate patients undergoing treatment for wet AMD
- determine if reduced flow to the choroid is a risk factor for developing wet AMD.
Eligibility
Inclusion Criteria (Groups with wet AMD):
- Adults aged 50 and older with clinical findings of treatment-naïve (never treated) neovascular AMD with active new blood vessel growth confirmed by clinical testing will be considered
Inclusion Criteria (Group with healthy eyes)
- No evidence of retinal disease
- Refractive error greater than +3.00 diopters or -7.00 diopters (glasses Rx)
- No recent eye surgery in the last 4 months
- No significant cataract to interfere with the quality of the imaging
Exclusion Criteria (All Groups):
- Inability to give informed consent
- Significant kidney disease
- Blood pressure greater than 180/110
- Previous macular laser treatment
- Inability to maintain stable fixation during OCT imaging
- Visual acuity worse than 20/200