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Effects of Cytotoxic Chemotherapy and PARP Inhibition on the Genomic Contexture of Ovarian Cancer

Recruiting
18 - 80 years of age
Female
Phase N/A
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Overview

EFFECTS OF CYTOTOXIC CHEMOTHERAPY AND PARP INHIBITION ON THE GENOMIC CONTEXTURE OF OVARIAN CANCER: TR_NACT_OV/17 In order to approach the above open questions, ultimately aiming in understanding the effects of cancer drugs on tumor biology and hence in selecting the proper drugs for the patients in the context of Precision Medicine, the objective of this study is to study the genomic characteristics of ovarian tumors before and after treatment with classic neoadjuvant chemotherapy (NACT) and with the more recently approved PARP inhibitor olaparib.

Eligibility

Inclusion Criteria:

  • ovarian cancer eligible for neoadjuvant chemotherapy

Exclusion Criteria:

-

Study details

Ovarian Cancer

NCT04752865

Hellenic Cooperative Oncology Group

26 January 2024

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