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Patient Blood Management in the Approach to Prosthetic Surgery [PBM(L4178)]

Recruiting
40 years of age
Both
Phase N/A

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Overview

We have been well guided in the "Good use of blood" during major surgery for many years, reaching a percentage of 4% of patients transfused after elective prosthetic operations. Valid patient blood management must provide for the possibility of limiting/zeroing the transfusion risk dependent on preoperative anemia, and the national guideline on PBM (Patient blood management) also underlines this Hypothesis and relevance

Description

We want to analyse patients from a diagnostic point of view (occult blood, diverticulitis, gastrorrhagia) and from the point of view of laboratory parameters (blood count, serum iron, transferrinemia, ferritinemia, transferrin saturation) in ordr to be able to suggest the best approach in preparation to the intervention.

We want to evaluate the effectiveness of this approach, considering the proposed treatments (ferric carboxymaltose, chelated iron, folic acid, sideremil vita) and the transfusion result (or not) obtained

Eligibility

Inclusion Criteria:

  • Candidates for prosthetic surgery
  • Patients of both sexes over 40 years of age
  • Hemoglobin values <12 g% for females and 13 g% for males
  • % transferrin saturation < 10%
  • Willingness and ability to provide informed consent.

Exclusion Criteria:

  • Patients with Mediterranean anemia
  • Patients with coagulation disorders
  • Patients who do not sign the consent form
  • Pregnant or breastfeeding women (self-declaration)
  • Minor aged

Study details

Anemia, Iron Deficiency

NCT05806437

Istituto Ortopedico Galeazzi

26 January 2024

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