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Extension Study to Evaluate Safety and Efficacy of Jaktinib in Patients With Active Ankylosing Spondylitis(AS)

Recruiting
18 - 65 years of age
Both
Phase 3

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Overview

The purpose of this study is to determine if Jaktinib is safe and effective in participants with active ankylosing spondylitis.

Eligibility

Inclusion Criteria:

  • The investigators concluded that the participants continued to benefit from treatment with Jaktinib.
  • The participants have been fully informed and voluntarily signed informed consent.
  • The participants completed the ZGJAK029 study for 16 weeks of treatment and visitation and had good compliance.
  • The interval between the participants' first dose and the last dose of ZGJAK029 ≤ 4 weeks.

Exclusion Criteria:

  • There were any grade ≥3 adverse events within 4 weeks prior to enrollment and no return to grade 1 or normal.
  • Within 4 weeks prior to enrollment, participants had the following infectious diseases: tuberculosis infection requiring treatment; HIV-positive, syphilis, HBV infection, HCV infection.
  • The investigators considered participants unsuitable for this study.

Study details

Ankylosing Spondylitis

NCT05861128

Suzhou Zelgen Biopharmaceuticals Co.,Ltd

26 January 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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