Overview
This prospective randomized double blinded study will be conducted to evaluate the effect of early pharmacologic intervention with calcitonin on the incidence or the severity of neuropathic pain after spinal cord injury
Description
Pain after spinal cord injury can be classified into five categories: musculoskeletal, visceral, at-level, above-level, and below-level neuropathic pain. Calcitonin has previously been shown to be effective in the management of acute pain following amputation, vertebral fractures and other neuropathic conditions. Also it was used in a previous study to prevent complex regional pain syndrome in severe hemiplegic patients after stroke
Eligibility
Inclusion Criteria:
- Patients aged ≥18 years, with spinal cord injury at any level and any degree of completeness in the early stage of trauma.
Exclusion Criteria:
- Intake of anticonvulsants medications.
- Evidence of neuropathic pain.
- Evidence of previous allergic reaction to calcitonin.
- Patients with renal, hepatic and cardiac dysfunction or neurological disorders .
- brain damage or major trauma to extremities or abdomen.