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Enhanced Recovery After Surgery (ERAS) Total Knee Replacement (TKR) With a Transitional Pain Service

Enhanced Recovery After Surgery (ERAS) Total Knee Replacement (TKR) With a Transitional Pain Service

Recruiting
18-65 years
All
Phase N/A

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Overview

A comparison of two anesthetic techniques for total knee replacements: (1) Peri-Articular Injection (PAI), local infiltration between the popliteal artery and capsule of the knee block (IPACK) and single-shot adductor canal block (ACB) vs. (2) PAI, IPACK and continuous adductor canal block catheter (ACC).

Description

Patients will be randomized to one of two groups: one group will receive a PAI, IPACK and single-shot adductor canal block; one group will receive PAI, IPACK and continuous adductor canal block catheter.

Eligibility

Inclusion Criteria:

  • Patients with osteoarthritis scheduled for a primary total knee arthroplasty with a participating surgeon
  • Planned use of regional anesthesia
  • Ability to follow study protocol
  • English speaking (secondary outcomes include questionnaires validated in English only)
  • Lives within one hour of the hospital
  • Has a smart phone

Exclusion Criteria:

  • Hepatic or renal insufficiency
  • Younger than 18 years old or older than 65 years ol
  • Patients undergoing general anesthesia
  • Allergy or intolerance to one of the study medications
  • BMI >40
  • Diabetes
  • American Society of Anesthesiologists (ASA) status III or IV
  • Chronic gabapentin/pregabalin use (regular use for longer than 3 months)
  • Patients with chronic pain (from a referral to chronic pain service) or a pain catastrophizing scale (PCS >30)
  • Patients with severe valgus deformity or flexion contracture
  • Patients unable to follow home catheter instructions and unwilling to go home with an infusing catheter
  • Patients who have no home caregivers in the event that a catheter is to be sent home with the patient
  • Patients with planned stay at rehab facility (to avoid medical device being tampered with at the rehab facility)
  • Non-English speakers (secondary outcomes include questionnaires validated in English only)

Study details
    Anesthesia

NCT03747146

Hospital for Special Surgery, New York

20 March 2024

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