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Circulating Tumor DNA to Monitor Response to Neoadjuvant Chemotherapy in Breast Cancer

Circulating Tumor DNA to Monitor Response to Neoadjuvant Chemotherapy in Breast Cancer

Recruiting
18-70 years
Female
Phase N/A
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Overview

Investigators aim to investigate whether circulating tumor DNA is a sensitive marker to evaluate patients' response to neoadjuvant chemotherapy

Description

Neoadjuvant chemotherapy(NAC) is traditionally for locally advanced disease, converting an inoperable to a resectable tumor.In recent years, it has become an option for patients of lower tumor stage to increase the possibility of breast conserving therapy. An effective method to monitor the response to NAC is important.

Eligibility

Inclusion Criteria:

  • Female patients undergoing NAC
  • Age: 18-70 yrs
  • Any menopausal status
  • Any hormal receptor status

Exclusion Criteria:

  • Metastasis discovered during NAC
  • Lost more than 2 blood samples during NAC and surgery

Study details
    Breast Cancer

NCT03260192

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

26 January 2024

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