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Helicobacter Pylori in Patients With Chronic Tonsillits Prepared for Tonsillectomy

Helicobacter Pylori in Patients With Chronic Tonsillits Prepared for Tonsillectomy

Not Recruiting
5-50 years
All
Phase N/A

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Overview

Tonsillar disorders are frequent In both pediatric and adult otolaryngological practice, . Numerous disorders that damage tonsillar tissue necessitate tonsillectomy. Tonsillectomy is typically required for recurrent tonsillitis. (Mani et al., 2019).

According to studies, the mucosa-associated lymphoid tissue (MALT) of the stomach and tonsillar tissue in the Waldeyer's ring are both lymphoid tissues (Ma et al., 2018).

One of the most prevalent and frequent conditions in otorhinolaryngology is chronic tonsillitis, which is mostly brought on by bacterial infection. Chronic tonsillitis attacks can affect not only the tonsillar tissue but also can contribute to the emergence and progression of systemic disorders (Alrayah.,2023).

A gram-negative, urease-producing bacterium called Helicobacter pylori colonizes the mucosa of the digestive tract. It has been linked to gastric malignancies, notably mucosa-associated lymphoid tissue (MALT) lymphoma, as well as gastric ulcers and duodenal ulcers (Kusters et al., 2006).

Eligibility

Inclusion Criteria:

  1. Age: 5 to 50 years.
  2. Of both sex.
  3. Diagnosed with chronic tonsillitis undergoing elective tonsillectomy

Exclusion Criteria:

  1. Patients on proton pump inhibitor or antibiotics 2 weeks before surgery .
  2. Immune-compromised patients.
  3. Patients with obstructive sleep apnea candidates for adenotonsillectomy

Study details
    Helicobacter Pylori Infection in Patients With Chronic Tonsillits

NCT06117956

Sohag University

30 January 2026

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