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Monitoring of Donor-specific Antibodies After Treatment With Immunoglobulins, Plasmapheresis and Rituximab in Lung Transplantation

Monitoring of Donor-specific Antibodies After Treatment With Immunoglobulins, Plasmapheresis and Rituximab in Lung Transplantation

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Phase N/A

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Overview

Single-arm, prospective observational study

Description

This is an observational study to monitor the treatment of donor-specific antibodies in lung transplant recipients with detection of donor-specific antibodies. All consented subjects will be approached for participation. The study will evaluate the effectiveness of the treatment protocol of donor-specific antibodies with Immunoglobulins or combined treatment with Immunoglobulins, Plasmapheresis and Rituximab after lung transplantation.

Eligibility

Inclusion Criteria:

  • all patients after lung transplantation with detection of donor-specific antibodies

Exclusion Criteria:

  • none

Study details
    Lung Transplantation
    Donor-specific Anti-human Leukocyte Antigen(HLA) Antibodies

NCT03798860

Hannover Medical School

26 January 2024

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