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Metastatic Pathologic Fractures, Short Term Results

Recruiting
years of age
Both
Phase N/A

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Overview

This is a single center prospective study to compare the short term results of prosthesis, nail and plate-screw surgeries for metastatic pathologic fractures.

Description

The most common bone tumor in elderly is metastatic bone tumors. With the prolonged life expectancy in cancer patients, the management of the metastases became an essential topic.

Pathological fractures should be examined and managed with a different perspective. They usually cannot be healed by conservative methods and require surgical intervention. The primary goals of surgical intervention are to relieve pain and mobilize the patient as soon as possible.

The aim of the study is to compare the short-term functional endoprosthetic recontruction, intramedullary nailing and open reduction internal fixation.

The primary tumor of the patient, applied chemotherapy and radiotherapy, Mirel risk score, Charlson comorbidity index, and PathFx 3.0 survival will be evaluated preoperatively.

The type of the operation will be decided at the multidisciplinary tumor council of ankara University.

Eligibility

Inclusion Criteria:

  • metastatic pathologic fracture
  • operated via endoprosthesis, intramedullary nail or plate & screws

Exclusion Criteria:

  • primary bone tumor
  • conservative management
  • neuromuscular disease
  • periprosthetic fractures
  • less than 1 month follow up

Study details

Pathologic Fracture, Bone Metastases, Metastatic Cancer

NCT05825456

Ankara University

26 January 2024

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