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Comparison of Different Methods for Intra- and Postoperative Pain Therapy in Thoracic Surgery

Recruiting
18 years of age
Both
Phase N/A

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Overview

The aim of the study is to determine which regional anaesthesiological technique (thoracic epidural analgesia or paravertebral block) is more suitable for thoracic surgery

Description

Thoracic interventions (lung operations) are associated with considerable postoperative pain, whereby an open surgical procedure via a skin incision (thoracotomy) is more painful than a minimally invasive endoscopic intervention (thoracoscopy). In order to reduce pain, a regional anaesthetic is administered during the induction of anaesthesia, which reduces pain both intraoperatively and postoperatively. In thoracic surgery, thoracic epidural analgesia (PDA) and paravertebral block (PVB) are the main regional anaesthesiological measures used, although it is unclear which of the two procedures is superior in terms of efficiency and effectiveness. Particularly intraoperatively, but also to some extent postoperatively, regional anaesthesia alone is usually not sufficient for pain management. Rather, additional systemic (i.e. intravenous) analgesics (especially opioids) are administered. Therefore, the amount of these additionally administered analgesics is a measure of the efficiency of the regional anaesthesia procedure.

Eligibility

Inclusion Criteria:

  • elective thoracic surgery
  • American Society of Anaesthesiologists (ASA) 1-3 status
  • written informed consent

Exclusion Criteria:

  • pregnancy
  • adipositas (bmi > 30)
  • cardiac arrhythmia
  • coagulation abnormalities
  • chronic pain
  • opiate abuses

Study details

Thoracic Surgery

NCT05208619

University Hospital, Bonn

26 January 2024

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