Overview
An inflammatory component associated with AMD has been highlighted by genetic associations of predisposition to AMD, as well as by the recently demonstrated link between AMD and periodontitis.
Some patients followed at the Fondation Adolphe de Rothschild Hospital for wet AMD seemed to show an improvement of neovascular activity (less need for intravitreal injections of anti-VEGF) after treatment of their sinusitis.
The investigators would therefore like to assess the link between AMD and sinusitis, an infection close to the site of AMD.
Eligibility
Inclusion Criteria:
- Age ≥ 18 years
- Patient followed and treated for at least 2 years for bilateral neovascular form of age-related macular degeneration (AMD)
- At least one eye treated with ≥ 6 intravitreal injections during the year preceding preinclusion
- Express consent to participate in the study
- Affiliated with or beneficiary of a social security plan
Exclusion Criteria:
- Persons referred to in articles L1121-5 to L1121-8 of the CSP (corresponding to all protected persons: pregnant women, parturients, nursing mothers, persons deprived of liberty by judicial or administrative decision, minors, and persons under legal protection: guardianship or curatorship).
- Severe myopia (> 6 diopters)
- Patient already being treated for acute or chronic sinusitis
- History of central serous chorioretinopathy or diffuse retinal epitheliopathy