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Building a Platform for Precision Anesthesia in the Geriatric Surgical Patient

Building a Platform for Precision Anesthesia in the Geriatric Surgical Patient

Recruiting
65 years and older
All
Phase N/A

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Overview

The research team is creating a foundational infrastructure in order to develop a precision medicine approach for geriatric patients who require surgery with anesthesia. The team plans to build the first of its kind comprehensive database of demographic and risk factor questionnaire responses, biobanked blood specimens, intraoperative electroencephalography (EEG), and inclusive cognitive testing throughout patient interaction starting at the preop appointment until a year later. This will be used to create a predictive model of periooperative neurocognitive disorders.

Eligibility

Inclusion Criteria:

  • At least 65 years old (inclusive)
  • Non cardiac general elective surgery
  • General anesthesia is expected for 2+ hours

Exclusion Criteria:

  • Alzheimer's
  • Dementia
  • Parkinson's
  • History of neurodegenerative diseases
  • Medication for depression (ie. Benzodiazepines)
  • Alcoholism
  • Discretion of PI

Study details
    Cognitive Decline
    Cognitive Change
    Cognitive Impairment
    Postoperative Delirium
    Anesthesia; Reaction
    Anesthesia; Adverse Effect

NCT03839784

Stanford University

26 January 2024

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