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IMMUNERECOV CONTRIBUTES TO IMPROVEMENT OF RESPIRATORY AND IMMUNOLOGICAL RESPONSE IN POST-COVID-19 PATIENTS.

IMMUNERECOV CONTRIBUTES TO IMPROVEMENT OF RESPIRATORY AND IMMUNOLOGICAL RESPONSE IN POST-COVID-19 PATIENTS.

Recruiting
18 years and older
All
Phase 3

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Overview

Background: COVID-19 left consequences in different organs from months to years requiring different types of rehabilitation. In fact, a severe loss in the lung function, and in the respiratory and peripheral muscle strength is commonly observed in post-COVID-19 patients. Objectives: Thus, the present study investigated whether 30 days of supplementation with a nutritional blend (ImmuneRecov®; composition: whey protein concentrate, astaxanthin, creatine, selenium, vitamin C, glutamic acid, tryptophan, magnesium) would help to minimize the respiratory (lung function) and muscular (respiratory and peripheral muscles) sequelae in post-COVID-19 patients.

Description

Background: COVID-19 left consequences in different organs from months to years requiring different types of rehabilitation. In fact, a severe loss in the lung function, and in the respiratory and peripheral muscle strength is commonly observed in post-COVID-19 patients. Objectives: Thus, the present study investigated whether 30 days of supplementation with a nutritional blend (ImmuneRecov®; composition: whey protein concentrate, astaxanthin, creatine, selenium, vitamin C, glutamic acid, tryptophan, magnesium) would help to minimize the respiratory (lung function) and muscular (respiratory and peripheral muscles) sequelae in post-COVID-19 patients. Design: This is a non-controlled open label prospective clinical study. Methods: Fifty-eight post-COVID-19 patients were recruited and twenty-four accepted to take the nutritional blend, while twenty-four did not accept but required to participate in the evaluations and 10 refused to participate. So, the patients were evaluated before the 14th day after hospital discharge and after 30 days of use of the nutritional blend or control (no supplementation).

Eligibility

Inclusion Criteria: The inclusion criteria encompassed post-COVID-19 patients with a

        confirmed COVID-19 diagnosis through a positive RT-PCR test, who also required
        hospitalization, meeting the criteria for moderate severity classification as defined by
        the World Health Organization (WHO). In summary, according to the WHO, moderate illness is
        characterized by individuals who exhibit signs of lower respiratory disease during clinical
        assessment or imaging and maintain an oxygen saturation level (SpO2) of ≥94% while
        breathing room air at sea level.
        Exclusion Criteria: Exclusion criteria included individuals discharged from the hospital
        for more than 14 days and those who initiated physical activity or began taking any dietary
        supplements or vitamins.

Study details
    Long Covid19
    Dietary Supplements
    Respiratory Tract Infections
    Inflammation

NCT06166030

Federal University of São Paulo

26 January 2024

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