Overview
The aim of this study is to test the efficacy of a nature-based cognitive intervention to restore cognitive function among women treated for breast cancer.
Description
Cognitive dysfunction is a kind of cluster of commonly reported neurotoxic symptoms following cancer diagnosis and treatment, especially chemotherapy. Our previous studies found that breast cancer patients and survivors had greater difficulties in performing attention, working memory, and executive function tasks and had persistent neural inefficiency of an executive network of the brain than disease and treatment counterparts.
The aim of this study is to test the efficacy of a nature-based cognitive intervention to restore cognitive function among women with cognitive complaints after breast cancer treatment. All participants will receive the initial screening to verify their cognitive status and then will be randomly assigned to the experimental or control group. The experimental group will receive a 4-week cognitive intervention by using a VR headset. Each VR content includes 10-12 video scenes with visual and auditory stimuli that were generated from nature.
Eligibility
Inclusion Criteria:
- Being treated with chemotherapy for breast cancer
- Having affirmative responses to three questions about cognitive problems and their impact on daily performance
- Having FACT-Cog scores of 58 or less
- Having Mini-Cog scores of 3 and higher
- Having the ability to read, understand or respond to questionnaires and cognitive assessment
- Being willing to participate and able to provide written informed consent
Exclusion Criteria:
- Having metastatic breast cancer
- Having Patient Health Questionnaire-2 score of 3 and higher
- Being diagnosed with neurological disorders such as dementia, multiple sclerosis, or traumatic brain injury
- Having epilepsy or seizure
- Having 'quite a bit' or 'extremely' severe level of nausea and vomiting
- Having visual or hearing impairments
- Having other problems that prevent them from wearing the VR headset