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Cerebral and Cognitive Markers of Treatment Resistance in Obsessive Compulsive Disorder

Cerebral and Cognitive Markers of Treatment Resistance in Obsessive Compulsive Disorder

Recruiting
18-70 years
All
Phase N/A

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Overview

This study aims to define individual profiles of treatment resistants in order to find indicators and predictors of the therapeutic response.

Eligibility

Inclusion Criteria:

  • Obsessive compulsive disorder diagnosed according to Diagnostic and Statistical Manual 5 criteria (patients will be included regardless of the severity and resistance of their pathology and their levels of executive functions)
  • Understand and accept the constraints of the study
  • Be a beneficiary or affiliated to a Health Insurance scheme

Exclusion Criteria:

  • Present one of the diagnoses according to the criteria of the DSM 5: schizophrenic disorders, substance abuse or dependence to a substance according to the criteria of the M.I.N.I. version 5.0 (Sheehan et al., 1998)
  • Generalized anxiety disorder, social anxiety, nicotine dependence and history of a major depressive episode are not exclusion criteria according to the M.I.N.I. version 5.0 (Sheehan et al., 1998)
  • Have a serious intercurrent pathology
  • Being a pregnant woman
  • Being a woman of childbearing age without effective contraception.
  • Being hospitalized under duress or on an outpatient basis in a care program
  • Being under judicial protection (reinforced curatorship, guardianship)

Study details
    OCD

NCT05843604

Centre Hospitalier Henri Laborit

26 January 2024

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