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Endoscopic Vacuum Therapy for Transmural Defects in the Upper Gastrointestinal Tract

Endoscopic Vacuum Therapy for Transmural Defects in the Upper Gastrointestinal Tract

Recruiting
18 years and older
All
Phase N/A
  • Technical (Original)
  • Simplified (AI rewritten)

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Overview

The goal of this observational study is to learn about the best indications and techniques regarding endoscopic vacuum therapy (EVT) in patients with a transmural defect in the upper gastrointestinal (GI) tract (e.g. anastomotic leakage, Boerhaave syndrome, iatrogenic perforation, other). The main questions it aims to answer are:

  • What is the success rate of EVT for transmural defects in the upper GI tract?
  • What are the best indications for EVT in the upper GI tract? (e.g. etiology, patient characteristics, defect characteristics)
  • What are the best techniques for EVT in the upper GI tract? (e.g. EsoSponge, VACStent, vacuum pressure, intraluminal/intracavitary) Participants will be asked for informed consent to retrospectively and prospectively collect data on EVT.

Eligibility

Inclusion Criteria:

  • Treated with EVT for anastomotic leakage after esophago-gastric surgery
  • Signed informed consent form
  • 18 years or older

Exclusion Criteria:

  • No signed informed consent

Study details
    Endoscopic Vacuum Therapy
    Anastomotic Leak
    Esophageal Perforation
    Esophageal Perforation
    Traumatic
    EsoSponge
    VACStent

NCT05606822

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

14 October 2025

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