Overview
This research aims to confirm that the therapeutic effect of EMDR is associated with changes in the interaction between cognitive function and emotional stimuli in PTSD patients compared to a controlled therapy in a randomized, single-blind study.On the other hand, this study aims to observe neuronal and cognitive correlates related to EMDR therapy compared to a control therapy.
This investigation would improve the understanding of the mechanisms of action of the EMDR, still unknown to date.
Eligibility
Inclusion Criteria:
- Patient diagnosed with PTSD according to DSM 5 criteria (APA 2013) related to a single traumatic event,
- Aged 18 to 65 years,
- Signed informed consent.
- Patient with social security affiliation or State Medical Aid (AME)
Exclusion Criteria:
- Neurological disorders
- No other major psychiatric disorders than PTSD (DSM 5)
- Severe and/or unstable somatic pathologies,
- Patient not affiliated with social security,
- Patient hospitalized under stress in psychiatric care at the decision of the state representative or in psychiatric care at the request of a third party,
- Patient under guardianship,
- Patient participating in parallel with other biomedical research,
- Change of antidepressant during the last three months,
- Patient not fluent in French
- MR-specific criteria for not inclusion:
- women of childbearing age without effective contraception or a positive pregnancy test,
- patients carrying pacemakers or electrical or electronic devices, clips or metal prostheses,
- subjects with neurological disorders, cerebral abnormalities or suffering from claustrophobia.