Overview
This study aims to prospectively collect the clinical and radiogical features to investigate the associations between the potential risk factors and secondary complications, adverse long-term functional outcomes, and death in patients with aneurysmal subarachnoid haemorrhage (aSAH).
Description
Aneurysmal subarachnoid haemorrhage (aSAH) is an acute cerebrovascular disease with high mortality and morbidity.
The early and delayed stages of brain injury after subarachnoid hemorrhage is usually accompanied by complications such as vasospams, delayed cerebral ischemia, rebleeding, hydrocephalus, and other organ damage, which determines a poor functional outcome. It is significantly important to investigate the association between the potential clinical and radiogical features with these complications and functional outcome after aSAH, including a well-known factor as total bleeding volume of subarachnoid hemorrhage.
In this study, the investigators prospectively collected a huge dataset of aSAH to fully investigate these correlation, including the association between radiomics features with these complications to prove the role of early radiogical factors. Then, the investigators will train models based on these potential contributing factors to highly predict these complications, disabilty, and death.
Eligibility
Inclusion Criteria:
- Subarachnoid hemorrhage was confirmed by CT;
- the CTA and DSA examination confirmed is aneurysm rupture caused by subarachnoid hemorrhage;
- bleeding after 24 hours of adept blood routine, biochemical function, blood coagulation function and craniocerebral CT;
- DCI was observed during 3 to 14 days after surgery;
- aneurysm clip by surgery or endovascular embolization.
Exclusion Criteria:
- Aneurysm rupture bleeding time more than 24 hours;
- by CTA and DSA examination found no intracranial aneurysm;
- Traumatic subarachnoid hemorrhage;
- the image data and check blood information is not complete;
- long-term anticoagulant drugs such as aspirin, wave dimensions;
- admitted to hospital with infectious diseases;
- merging other intracranial vascular malformation.