Overview
This study is a dynamically adjustable prospective longitudinal study designed to capture biospecimen (biopsy, blood, surgical) and multimodal treatment (imaging, dosimetry, clinical) data before, during, and after treatment with definitive-intent standard of care (SOC) radiotherapy for patients with locally advanced cervical and pancreatic cancer.
Eligibility
Inclusion Criteria:
- Confirmation of intent to receive standard of care radiotherapy for one of the
following diagnoses:
- Locally advanced or metastatic cervical cancer
- Locally advanced or metastatic pancreatic cancer
- ECOG performance status ≤ 2
- At least 18 years old
- Able to understand and willing to sign an IRB-approved written informed consent document
Exclusion Criteria:
- Co-enrollment to another therapeutic study receiving investigational agent
- Any issue (medical, anatomic, other) that might preclude safe acquisition of biospecimens at the discretion of the treating physician