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Pelvic Floor Muscle Training in the Treatment of Erectile Dysfunction

Recruiting
30 - 70 years of age
Male
Phase N/A

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Overview

Erectile dysfunction affects about 40% of all men above the age of 40 and the prevalence increases with increasing age. It is not possible to cure the condition as current forms of treatment are aimed solely at improving symptoms. Treatment options today include medications, injection therapy, and vacuum pumps, among others. However, pelvic floor muscle training is a natural, inexpensive, and non-invasive form of treatment that is used to a limited extent.

Theoretically, a strengthening of the pelvic floor muscles can help increase the intracavernous pressure and thereby the hardness of the erection. Furthermore, tense pelvic floor muscles can help compress pelvic veins and reduce blood flow away from the penis which prolongs the erection. Finally, it is possible that pelvic floor muscle training can contribute to an increased blood supply to the pelvic floor and the penis which will have positive effects in relation to both the integrity of the penile tissue and the physiological erection mechanism itself.

This study aims to investigate the effect of pelvic floor muscle training in men with erectile dysfunction.

The study hypothesis is that pelvic floor training can provide a clinically significant improvement in the erection function at individual patient level

Eligibility

Inclusion Criteria:

  • Erectile Dysfunction for more than 6 months
  • IIEF-EF score < 25
  • In a stable heterosexual relationship in minimum of 3 months (since all questionnaires are only validated for heterosexuals)

Exclusion Criteria:

  • Known psychiatric, neurological, and/or endocrine disorders (including hypogonadism with total testosterone <12 nmol / l)
  • Traumatic nerve damage
  • Diabetes
  • Previous surgery or radiotherapy in the pelvic region
  • Nerve disorders that prevent nerve connection to the pelvic floor muscles
  • Severe heart disease in the form of unstable angina, NYHA class > II heart failure, uncontrolled arrhythmia or severe symptomatic and/or severe valvular disease
  • Use of anti-androgen drugs Peyronie's disease and/or previous cases of priapism
  • Alcohol overconsumption (more than 21 items per week)

Study details

Erectile Dysfunction

NCT05385822

Herlev and Gentofte Hospital

26 January 2024

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