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C-SMART: Cognitive Strategies, Mindfulness, and Rehabilitation Therapy for Patients With Primary Brain Tumors

C-SMART: Cognitive Strategies, Mindfulness, and Rehabilitation Therapy for Patients With Primary Brain Tumors

Non Recruiting
18 years and older
All
Phase N/A

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Overview

The primary aims of this mixed-methods trial are to test the feasibility and acceptability of the novel Cognitive Strategies, Mindfulness, and Rehabilitation Therapy (C-SMART) delivered via telehealth to patients with primary brain tumors and mild neurocognitive disorder (mNCD).

Eligibility

Inclusion Criteria:

  • Adults with a primary brain tumor confirmed by histology or neuro-oncologist's report
  • At least one domain of neurocognitive function ≥ 1.5 SD below estimate premorbid functioning or ≥ 1.5 SD below population mean
  • Karnofsky's Performance Status (KPS) score > 40
  • ≥ 1 month out of radiation therapy
  • Ability to read, speak, and understand English

Exclusion Criteria:

  • Inability to attend virtual sessions
  • Inability to understand and provide informed consent
  • Presence of clinically significant insomnia

Study details
    Glioma
    Mixed
    Mild Neurocognitive Disorder
    Brain Tumor

NCT05984667

Virginia Commonwealth University

20 August 2025

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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