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Immune Treatment of Brain Metastasis of Lung Cancer Combined With Large-segmentation Precision Radiotherapy

Immune Treatment of Brain Metastasis of Lung Cancer Combined With Large-segmentation Precision Radiotherapy

Recruiting
18 years and older
All
Phase 2
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  • Simplified (AI rewritten)

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Overview

This is a prospective multicenter clinical study. This study aims to construct an auxiliary decision-making system for lung cancer immunotherapy combined with radiotherapy by fusing three modes of imagomics, clinicopathological features, and molecular pathological features.

Eligibility

Inclusion Criteria:

  • Age ≥ 18 years of age on day of signing informed consent
  • Histopathology confirmed non-small cell lung cancer
  • Asymptomatic brain metastases
  • EGFR/ALK ROS1 driver gene mutation negative
  • RECIST 1.1 based available assessment of lesions
  • ECOG 0-1
  • Brain metastases 1-4
  • Single lesion ≤4cm

Exclusion Criteria:

  • Patients with contraindication of chemotherapy Pregnant or breast feeding women

Study details
    Non Small Cell Lung Cancer

NCT05584267

Hunan Province Tumor Hospital

8 June 2024

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