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Cancer Survivor Cardiomyopathy Detection

Recruiting
18 - 99 years of age
Both
Phase N/A

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Overview

The purpose of this study is to improve the cardiovascular care of adult cancer survivors. The goal is to obtain the data necessary to plan and develop a nation-wide network of a screening program that can help provide cost-effective and long-term monitoring.

Description

The primary objective of this study is to define the diagnostic performance and optimal cutoffs of AI-ECG and NT-pro-BNP for the detection of left ventricular dysfunction (LVD, defined as a left ventricular ejection fraction (LVEF) <50%) in cancer patients at 1 year after completion of anthracycline-based chemotherapy.

Eligibility

Inclusion Criteria:

  • ≥18 years of age prior to enrollment and anthracycline start date
  • diagnosis of breast cancer, lymphoma, or sarcoma with either planned or at 1 year after completion of anthracycline therapy, including patients from 6-12 months and greater than 1 year post-anthracycline exposure.

Exclusion Criteria:

  • LVEF <50% or prior confirmed history of cardiomyopathy, heart failure, persistent atrial fibrillation, left bundle branch block, or paced rhythm
  • Individuals with pacemakers, defibrillators, or other implanted electronic devices
  • Inability/unwillingness of individual to give written informed consent

Study details

Cardiovascular Diseases, Cancer

NCT05201014

Mayo Clinic

14 January 2025

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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