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Clinical Study Evaluating Beta Blockers Use and Fracture Risk in Patients With Primary Osteoporosis

Clinical Study Evaluating Beta Blockers Use and Fracture Risk in Patients With Primary Osteoporosis

Recruiting
50 years and older
All
Phase 3

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Overview

Clinical study evaluating selective or nonselective beta blockers use and fracture risk in patients with primary osteoporosis

Description

Clinical study evaluating selective or nonselective beta blockers use and if there is fracture risk in patients with primary osteoporosis

Eligibility

Inclusion Criteria:

  • • Male & female osteoporotic patient aged ≥ 50 years
    • Hypertensive & normotensive patients
    • BMD T-score ≥ 2.5 or more SD below peak bone mass

Exclusion Criteria:

  • Patients on drugs that may improve osteoporosis disease state such as:
    • Angiotensin converting enzyme inhibitor (ACEI) or Angiotensin receptor blockers (ARBs), Thiazide diuretic, Nitrates, Spironolactone, Statins.

Patients on drugs that may worsen osteoporosis disease state such as:

        • Corticosteroids, Loop diuretics, Anticonvulsants, Antidepressants, Aromatase inhibitors,
        Thyroid replacement therapy and Proton pump inhibitors.

Study details
    Beta Blocker Toxicity

NCT04704947

Sherief Abd-Elsalam

26 January 2024

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