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Vitamin B12 and Dextrose for Median Nerve Hydrodissection

Vitamin B12 and Dextrose for Median Nerve Hydrodissection

Recruiting
20-80 years
All
Phase N/A

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Overview

Carpal tunnel syndrome is the most common peripheral entrapment neuropathy of the upper limb. Previous experiments found that ultrasound-guided median nerve hydrodissection with 5% dextrose water could ameliorate the condition of carpal tunnel syndrome. Oral administration of vitamin B 12 had been reported to reduce the discomfort from peripheral neuropathy although the level of evidence is not strong. This prospective, double-blind randomized control trial aims to compare the effects of different kinds of the injection agents on carpal tunnel syndrome.

Eligibility

Inclusion Criteria:

  • Age between 20-80 year-old.
  • Diagnosis (carpal tunnel syndrome) was confirmed using an electrophysiological study.

Exclusion Criteria:

  • Previously undergone wrist surgery or steroid injection for CTS
  • Thrombocytopenia
  • Coagulopathy
  • Inflammation status
  • Polyneuropathy
  • Brachial plexopathy
  • Cervical radiculopathy
  • Autoimmune disease
  • Malignancy
  • Pregnancy

Thoracic outlet syndrome

Study details
    Carpal Tunnel Syndrome

NCT05423028

National Cheng-Kung University Hospital

26 January 2024

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