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Motor Plasticity, Intermittent Hypoxia and Sleep Apnea

Motor Plasticity, Intermittent Hypoxia and Sleep Apnea

Non Recruiting
18 years and older
All
Phase N/A

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Overview

The purpose of this study is to learn about the effect of sleep apnea and low oxygen on muscle strength and lung function in people with chronic spinal cord injury.

Eligibility

Inclusion Criteria:

  1. Age 18 or older,
  2. Chronic (≥ 1-year post-injury), non-progressive SCI,
  3. Asia Impairment Scale (AIS) C or D,
  4. Resting Saturated oxygen (SaO2) ≥ 95%,
  5. Cervical injury (C5-C8)

Exclusion Criteria:

  1. Currently hospitalized,
  2. Resting heart rate ≥120 Beats per minute (BPM),
  3. Resting systolic blood pressure >180 mmHg,
  4. Resting diastolic Blood Pressure >100 mmHg,
  5. Self-reported history of unstable angina or myocardial infarction within the previous month,
  6. OSA that is being treated with positive airway pressure therapy,
  7. Women who know or suspect they may be pregnant or who may become pregnant,
  8. Known underlying lung disease,
  9. Pregnant Women,
  10. Prisoners,
  11. Unable to consent

Study details
    Sleep Apnea
    Obstructive
    Spinal Cord Injuries
    Hypoxia

NCT04017767

University of Miami

20 August 2025

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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