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INvestigational Study Into Transplantation of the Uterus

INvestigational Study Into Transplantation of the Uterus

Non Recruiting
24-38 years
Female
Phase N/A
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Overview

Observational study on cohort of 10 women undergoing uterine transplantation using deceased donors

Eligibility

Inclusion Criteria:

  1. Female
  2. Age - 24-38 (or 40 if eggs frozen <38)
  3. AUFI
    1. Normal length vagina
    2. No renal pathology
  4. BMI <30kg/m2
  5. ASA grade I
  6. Meet psychological criteria
  7. Meet HFEA criteria for IVF
  8. Eligible for NHS treatment
  9. Speak fluent English

Exclusion Criteria:

  1. Unsuccessful oocyte retrieval (<10 good quality embryos)
  2. Previous multiple/significant surgeries
  3. Severe endometriosis
  4. Cancer patients <5 years in remission
  5. Previous living childbirth, adopted child or child born through surrogacy
  6. HIV or Hepatitis B / C positive
  7. Skin or intestinal neovagina

Study details
    Mayer-Rokitansky-Kuster Syndrome
    Asherson's Syndrome
    Postpartum Hemorrhage
    Cervical Cancer

NCT04244409

Womb Transplant UK

20 August 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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