Overview
The investigators aim to collect breast-milk and feces from the participants, and apply culture techniques as well as omics sequencing technology to probe into the microbial and metabolomic signature of the specimens.
Eligibility
Inclusion Criteria:
- healthy pregnant women aged between 20y and 40y.
- Vaginal birth
- BMI<23.5 before pregnancy
- Infants' birth weight, between 2500g and 4000g.
Exclusion Criteria:
- gestational diabetes
- diagnosis of depressive disorder during pregnancy
- gestational hypertension
- diagnosis of other diseases during pregnancy
- Under probiotics or antibiotic treatment from 3 months prior to pregnancy till 3 months after delivery
- histrory of smoking and drinking alcohol
- history of diarrhea from 3 months prior to pregnancy till 3 months after delivery