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Methylene Blue Mouthwash for the Treatment of Oral Mucositis Pain in Patients With Cancer

Methylene Blue Mouthwash for the Treatment of Oral Mucositis Pain in Patients With Cancer

Non Recruiting
18 years and older
All
Phase 3
  • Technical (Original)
  • Simplified (AI rewritten)

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Overview

This phase III trial compares the effect of methylene blue mouthwash to standard of care mouthwash for the treatment of oral mucositis pain in patients with cancer. Using methlylene blue mouthwash may improve oral pain in patients with oral mucositis related to cancer and/or cancer treatments compared to usual standard of care.

Eligibility

Inclusion Criteria:

  • Active cancer diagnosis
  • Admitted to the inpatient setting
  • Pain related to oral mucositis
  • Experiencing oropharyngeal pain
  • Able to provide informed consent

Exclusion Criteria:

  • Pediatric age (under 18 years old)
  • Pregnant or nursing women
  • Any contraindication to methylene blue including severe hypersensitivity to methylene blue and patients with glucose-6-phosphate dehydrogenase deficiency (G6PD) due to the risk of hemolytic anemia

Study details
    Hematopoietic and Lymphoid System Neoplasm
    Malignant Solid Neoplasm
    Stomatitis

NCT05878405

Mayo Clinic

20 August 2025

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FAQs

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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