Overview
This cohort study aims to investigate the clinical efficacy and safety of Hybrid APC for treatment of gastric low grade intramucosal neoplasia.
Description
This cohort study aims to investigate the clinical efficacy and safety of Hybrid APC for treatment of gastric low grade intramucosal neoplasia. Successful ablation is defined as no evidence of local recurrence at 12 months after HybridAPC upon follow up endoscopy. This is defined as absence of LGIN, HGIN and cancer in biopsies obtained at all locations during followup endoscopy.
Eligibility
Inclusion Criteria:
- Low grade intraepithelial neoplasia of stomach with sizeā¤20 mm
- Endoscopic diagnosis suspected gastric LGIN with biopsy confirmed gastric LGIN
- Endoscopic appearance according to Paris classification of Type 0-IIa, IIb or IIc
- Patients with informed consent
Exclusion Criteria:
- Patients who had previous endoscopic treatment (including APC, EMR, ESD) for gastric LGIN, HGIN or gastric carcinoma.
- Endoscopic evidence of ulcer
- Biopsy confirmed HGIN
- Endoscopic diagnosis suspected HGIN while biopsy confirmed LGIN
- Pregnancy
- informed consent not available