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The Effect of a Dietary Supplement Rich in Nitric Oxide in Patients Diagnosed With Primary Ciliary Dyskinesia.

Recruiting
4 - 99 years of age
Both
Phase N/A

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Overview

The purpose of this study is to determine the effect of a dietary supplement rich in nitric oxide (NO) on nasal nitric oxide and fractional exhaled nitric oxide (FeNO),on ciliary beat frequency assessed by high-speed digital video microscopy and on lung function assessed by spirometry in normal patients and patients with Primary ciliary dyskinesia (PCD).

Eligibility

Inclusion Criteria:

Experimental group:

  • PCD patients

Control Group:

  • patients with no known chronic lung disease
  • 18 years to 99 years

Exclusion Criteria(both PCD patients and control group):

  • any other pulmonary co-morbidities and diseases entities like cystic fibrosis, nasal sinus surgery, nasal sinus hypoplasia/aplasia, deviated nasal septum, nasal polyps and with upper respiratory tract infection
  • patients allergic to beet
  • a known prolonged bleeding disorder.

Study details

Primary Ciliary Dyskinesia

NCT04489472

The University of Texas Health Science Center, Houston

26 January 2024

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