Overview
The effect of mailing FIT with the invitation on participation and colonoscopy rates will be evaluated in a randomized controlled trial conducted in the Centre-Val de Loire (CVL) region, involving 64,000 people from the population eligible for colorectal cancer population-based organised screening program (CRC-PBOSP).
In the "C" control group, invitations, test delivery and reminders will be carried out in accordance with the CRC-PBOSP rules at the time of the study.
Intervention group "B" will evaluate two experimental modes of invitation with direct home mailing of the test:
- Method "B1": invitation with test sent to home without prior information letter
- Method "B2": information letter followed by invitation with test sent home, designed to optimize participation by first-time subjects (aged 50-51) invited to the CRC-PBOSP for the first time.
Ancillary studies will focus 1/ on acceptability of this intervention (qualitative study on a few general practitioners, gastroenterologists and invitees), 2/ on social and geographical inequalities of participation on a subsample of individuals included in EXPEDIT study using ecological indices (EDI, SCALE).
Eligibility
Inclusion Criteria:
- 50 to 74 years old
- Resident of Centre Val de Loire French area
- Eligible for CRC screening invitation within the biennal CRC-PBOSP during the inclusion period
- Affiliated to the health insurance scheme
Exclusion Criteria:
- CRC screening exclusion criteria notified to CRCDC-CVL in a previous screening round (family or personal history of CRC/adenoma, inflammatory bowel disease)
- Colonoscopy in the previous 5 years)
Subjects refusing data transmission to research team will be excluded from statistical
analyses.