Image

Brain, Psychological and Epigenetic Determinants for Optimizing the Treatment of Chronic Low Back Pain

Recruiting
18 - 75 years of age
Both
Phase N/A

Powered by AI

Overview

The goal of this observational study is to better understand the role of the brain in chronic low back pain patients.

Description

Chronic pain affects millions of people worldwide, and the main cardinal sign of any arthritis condition is pain. Several arthritis conditions can cause chronic low back pain (CLBP).The mechanisms that contribute to CLBP are not yet fully understood, but considering the role of the brain in the context of chronic pain, it is only logical to investigate structural and functional brain properties in CLBP, in order to improve diagnosis and treatment of this condition.

Eligibility

Inclusion Criteria:

  • Low back pain (≥ 6 months) with or without pain radiating to the legs or radiating to the neck
  • Positive medial branch blocks, suggesting that the pain originates from the lumbar facet joints
  • Average pain intensity of ≥ 3/10 in the 24-hour period before the initial visit
  • Pain primarily localized in the lower back

Exclusion Criteria:

  • Inadequate pain relief or relief of less than three months following selective thermoablation of medial lumbar branches by radiofrequency
  • Neurological, cardiovascular, or pulmonary disorders
  • Comorbid pain syndrome
  • History of surgical intervention in the back
  • A corticosteroid infiltration within the past year
  • Pregnancy (current or planned during the course of the study)
  • Contra-indication to Magnetic Resonance Imaging (MRI)

Study details

Chronic Low-back Pain

NCT05963451

Université de Sherbrooke

26 January 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.