Image

Impact of a Sensory Rehabilitation Program on Olfactory-gustatory Alterations in Patients Treated With Chemotherapy for Haematological Cancer

Impact of a Sensory Rehabilitation Program on Olfactory-gustatory Alterations in Patients Treated With Chemotherapy for Haematological Cancer

Recruiting
18-75 years
All
Phase N/A

Powered by AI

Overview

Proposition of a sensory rehabilitation program that could reduce the olfactory-gustatory alterations in patients who have been treated with chemotherapy for Haematological Cancer, and also improve their life quality, psychological well-being, and nutrition.

Description

Disturbances in taste and smell affect a considerable proportion of patients treated with chemotherapy. In hematology, dysgeusia depends on the type pathology and the treatments themselves. It impacts the quality of life, leads to significant emotional and social consequences, affects the intake, weight and nutritional status of patients.

Olfactory-taste disorders can be assessed using subjective and objective tests. There are no international clinical recommendations for the management of taste and olfactory disturbances associated with chemotherapy in hematological cancers. Also, this study proposes to evaluate a taste and olfaction rehabilitation program based on national standards and recent research. It will help fill gaps in the assessment and management of patients treated for Haematological cancer.

Hypothesis is that this sensory rehabilitation program should make it possible to reduce the olfactory-gustatory changes in patients who have been treated with Chemotherapy for Haematological cancer and significantly improve their quality of life, their psychological well-being and their nutrition.

Eligibility

Inclusion Criteria:

  • Age between 18 and ≤ 75 years old
  • Patient with olfactory or gustatory disorders
  • Patient who has completed chemotherapy for haematological cancer

Exclusion Criteria:

  • Eating disorder known prior to anti-cancer treatment, bulimic, anorexic or binge eating disorder (DSM-V criteria)
  • Refusal to sign the free and informed consent
  • Hypersensitivity to one of the components of liposomal sprays (Liposaliva® or liponasal®)
  • COVID + patient in the previous 3 months
  • Performance status ECOG 3 or 4
  • Patient included in another clinical trial modifying taste / olfaction
  • Artificial nutrition post-chemotherapy
  • Known food allergies
  • Having a reading level in French that may interfere with a good understanding of the protocol and the questionnaires
  • Presenting visual or hearing deficits uncorrected to normal and which may affect the proper completion of the questionnaires
  • Patient under curatorship or tutorship.
  • Patient deprived of liberty
  • Pregnant or breastfeeding patient
  • Not be affiliated with a French social security scheme or beneficiary of such a scheme

Study details
    Multiple Myeloma
    Olfactivo-gustatory Disorder
    Lymphoma
    Haematological Cancer

NCT04716153

University Hospital, Montpellier

23 June 2025

Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.