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Recording of Intraoperative Spinal Cord Stimulation and Monitoring

Recording of Intraoperative Spinal Cord Stimulation and Monitoring

Recruiting
18 years and older
All
Phase N/A

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Overview

Opioid overdose suppresses brainstem respiratory circuits, causes apnea, and may result in death. Epidural electrical stimulation (EES) at the cervical spinal cord facilitated motor activity in rodents and humans, and we hypothesized that EES of the cervical spinal cord could antagonize opioid-induced respiratory depression in humans. In this study, we will stimulate the spinal cord during surgery and assess its effects on respiratory function in human patients.

Eligibility

Inclusion Criteria:

  • Any patients undergoing brain or spinal cord surgery where spinal neuromonitoring is utilized.

Exclusion Criteria:

  • none

Study details
    Cervical Stenosis
    Disk
    Herniated
    Spondylosis

NCT05356286

University of California, Los Angeles

25 January 2024

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