Overview
To evaluate safety and the ocular hypotensive effect of STN1012600 ophthalmic solution 0.002% alone or in combination with Timolol ophthalmic solution 0.5% for 52 weeks in subjects with open angle glaucoma or ocular hypertension.
Eligibility
Inclusion Criteria:
- 18 years of age or older.
- Diagnosis of OAG or OHT in both eyes, or one eye with OAG and the other with OHT.
- Corrected Visual Acuity of +0.60 logMAR (Decimal visual acuity 0.3) or better in each eye.
Exclusion Criteria:
- Presence of any active severe external ocular disease, inflammation, or infection of the eye and/or eyelids in either eye.
- History of severe ocular trauma in either eye.
- Any condition that prevents clear visualization of the fundus in either eye.
- Known allergy, hypersensitivity or contraindications to any components of the study medications or other study related procedures/medications.
- History of ocular surgery specifically intended to lower IOP in either eye.
- History of keratorefractive surgery in either eye.
- Females who are pregnant, nursing, or planning a pregnancy.
- Subjects with known or suspected drug or alcohol abuse.
- Participation in other investigational drugs or device clinical trials within 30 days prior to Screening.
- Any decision by the Investigator to terminate a subject in screening or declare any subject ineligible for any sound medical reason.