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A Study to Learn About the Study Medicine (Called Abrocitinib) in Adult Patients With Moderate to Severe Atopic Dermatitis

A Study to Learn About the Study Medicine (Called Abrocitinib) in Adult Patients With Moderate to Severe Atopic Dermatitis

Non Recruiting
18 years and older
All
Phase N/A

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Overview

The purpose of this non-interventional observational study is to learn about the safety and effects of the medicinal product (called Abrocitinib) for the potential treatment of moderate to severe atopic dermatitis (AD). AD is a long-lasting disease that causes redness and irritation of the skin. This non-interventional study is seeking participants who is eligible for Abrocitinib treatment according to the summary of product characteristics (SmPC):

  • Are aged at least 18 years old
  • Have a confirmed diagnosis of AD by a skin doctor
  • Decide to start treatment with Abrocitinib as part of routine clinical practice
  • Have a personally signed and dated informed consent document. This is used to indicate that the patient has been informed of all pertinent aspects of the study and data privacy aspects

Participants will take the medicinal product as prescribed in the real-world setting. We will examine the experiences of people receiving Abrocitinib. This will help us determine if the medicinal product is effective and safe. Participants will take part in this study for 3 months. During this time, participants will be followed up from the date of their first Abrocitinib prescription for 12 months. During this non-interventional study, some participants may switch to other therapies after their initial Abrocitinib therapy. We will follow these participants further when they switch therapy to monitor their experiences. Participant documentation is expected quarterly as per standard clinical practice.

Eligibility

Inclusion Criteria:

  • Patients aged ≥18 years
  • Confirmed diagnosis of AD by dermatologist prior to study inclusion
  • Patient for whom the decision to initiate treatment with Abrocitinib was made as part of routine clinical practice
  • Patient is eligible for Abrocitinib treatment according to Summary of Product Characteristics (SmPC)
  • Evidence of a personally signed and dated informed consent document indicating that the patient has been informed of all pertinent aspects of the study

Exclusion Criteria:

  • Contraindications according to SmPC
  • Receipt of any investigational drug within 3 months or longer if required according to wash-out period prior to inclusion or participation in a clinical trial during observation period
  • Patients who have received previous treatment with Abrocitinib within 3 months before study inclusion
  • Patients who are investigational site staff members or patients who are Pfizer employees directly involved in the conduct of the study
  • Patients who are unable to consent

Study details
    Dermatitis
    Atopic

NCT05250115

Pfizer

20 August 2025

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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