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Temporal Relationship Between Motor Fluctuations and Nonmotor Fluctuations

Recruiting
years of age
Both
Phase N/A

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Overview

The purpose of this study is to determine the temporal relationship between motor fluctuations and non-motor fluctuations in persons with Parkinson's disease.

Observational study case-only

Description

Objectives

  1. how many patients will experience motor or nonmotor fluctuation during follow-up period?
  2. in how many patients, does motor fluctuation precede nonmotor fluctuation?
  3. in how many patients, does nonmotor fluctuation precede motor fluctuation?

Participants: persons with Parkinson disease in early stage who does not have motor or nonmotor fluctuation

Recruitment period: 3 years from the commencement of the study Follow-up period: 3 years for each participants

Eligibility

Inclusion Criteria:

  • clinical diagnosis of Parkinson disease by United Kingdom Parkinson's Disease Society Brain Bank criteria
  • early stage

Exclusion Criteria:

  • dementia (MMSE<26)
  • persons who refuse participating

Study details

Parkinson Disease

NCT02060695

Seoul National University Hospital

25 January 2024

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