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Natives Engaged in Alzheimers Research - 'Ike Kupuna

Recruiting
50 - 75 years of age
Both
Phase N/A

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Overview

This study will conduct a group randomized trial to test the effects of a hula-based intervention in improving vascular risk factors for ADRD and cognitive complaints and function over 12 months.

Description

This study will conduct a pragmatic group-randomized trial (GRT) with NHPIs aged 50-75 years with at least 1 of 4 modifiable vascular risk factors for ADRD (hypertension, hyperglycemia, obesity, or dyslipidemia) and either SCI or MCI using a wait-list control design to test the effects of the hula-based intervention. The primary outcomes will be vascular risk factors for ADRD and subjective cognitive complaints. Secondary outcomes will include measures of cognitive performance, physical function, and mental health.

Eligibility

Inclusion Criteria:

  1. self-reported Native Hawaiian or other Pacific Islander ancestry;
  2. ages 50+ but not older than 75 (optimal age range for preventing future dementia in people with cognitive impairment, above 75 is not likely to benefit from this study given their advance age);
  3. has subjective cognitive impairment (SCI) or mild cognitive impairment (MCI);
  4. have a diagnosis of hypertension, diabetes, dyslipidemia, or obesity (body-mass-index ≥ 30 kg/m2);
  5. physically able and willing to engage in moderate physical activity necessary for Hula; and
  6. physician's approval to participate in moderate physical activity

Exclusion Criteria:

  1. currently pregnant;
  2. already actively practicing Hula at least once per week; or
  3. clinical diagnosis of ADRD (mild to severe); or
  4. current diagnosed major depressive disorder at moderate or greater stage, or moderate or greater depression on the Center for Epidemiological Studies Depression Scale (CES-D).

Study details

Mild Cognitive Impairment, Subjective Cognitive Impairment

NCT05534607

University of Hawaii

25 January 2024

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