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Florida Cerebrovascular Disease Biorepository and Genomics Center

Florida Cerebrovascular Disease Biorepository and Genomics Center

Recruiting
18 years and older
All
Phase N/A

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Overview

The purpose of this study is to create a state-wide biorepository and resource center for cerebrovascular diseases in Florida, which will include collecting medical history information and blood from subjects affected by cerebrovascular disease. The information and blood samples collected may be used in future research for the study of cerebrovascular disease and to learn about, prevent or treat other health problems.

Eligibility

Inclusion Criteria:

        • Affected subjects with diverse cerebrovascular conditions, including, but not limited to,
        ischemic stroke, transient ischemic attack (TIA), intracerebral hemorrhage (ICH),
        aneurysmal subarachnoid hemorrhage (aSAH), vascular dementia (VAD), anoxic brain injury,
        unruptured intracranial aneurysm (UIA), cavernous malformation, arteriovenous malformations
        (AVM), carotid and vertebral arterial dissections, symptomatic and asymptomatic cervical
        carotid artery atherosclerotic stenosis, non-aneurysmal perimesencephalic subarachnoid
        hemorrhage (naSAH), cerebral venous thrombosis (CVT), moyamoya disease, fibrosmuscular
        dysplasia (FMD), non-traumatic, angiography-negative subarachnoid hemorrhage,
        leukoaraiosis, arteriovenous fistula, reversible cerebral vasoconstriction syndrome (RCVS),
        and CADASIL.
        Exclusion Criteria:
        • All patients with the following known or suspected virulent microorganisms causing an
        active or latent infection will be excluded from the study:
          -  Human immunodeficiency virus (HIV);
          -  Any viral hepatitis;
          -  West Nile virus (WNV);
          -  Influenza virus;
          -  Tuberculosis (TB);
          -  Any bacteremia;
          -  Any fungemia;
          -  Any prionopathy.

Study details
    Cerebrovascular Disease
    Ischemic Stroke
    Transient Ischemic Attack
    Intracerebral Hemorrhage
    Aneurysmal Subarachnoid Hemorrhage
    Vascular Dementia
    Anoxic Brain Injury
    Unruptured Intracranial Aneurysm
    Carotid Artery Stenosis Symptomatic
    Asymptomatic Carotid Artery Stenosis
    Non-Aneurysmal Perimesencephalic Subarachnoid Haemorrhage
    Cerebral Venous Thrombosis
    Moyamoya Disease
    Fibromuscular Dysplasia
    Subarachnoid Hemorrhage
    Leukoaraiosis
    Arteriovenous Fistula
    Reversible Cerebral Vasoconstriction Syndrome
    CADASIL

NCT05491980

Mayo Clinic

25 January 2024

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