Overview
Researchers are doing this study to look at whether sexual health counselling and using non-hormonal moisturizer at the start of ovarian suppression may be able to prevent or reduce side effects such as vaginal dryness and sexual dysfunction. Researchers will compare how effective this prevention intervention works compared to the usual approach, which is to treat these side effects after they start. All participants will also complete surveys about their sexual health. This information will help researchers learn more about the sexual health of women with breast cancer receiving ovarian suppression.
Description
50 premenopausal or perimenopausal women who are receiving ovarian suppression as part of their breast cancer treatment will be randomized to upfront intervention vs at the time of symptom development (standard of care). Patients will have subjective and objective monitoring of vaginal dryness and sexual dysfunction.
Eligibility
Inclusion Criteria:
- Breast cancer patients with hormone receptor positive breast cancer , stage 0-III
- Patients are being initiated on ovarian suppression and endocrine therapy or are within 2 weeks of initiation
- Women, 18 years of age or older
- Premenopausal or perimenopausal women who have either been pregnant or had at least one menstrual period in the last 24 months or have/had an IUD in place
Exclusion Criteria:
- Postmenopausal women who have been without a period for ≥ 2 years
- Not initiated on both ovarian suppression and endocrine therapy
- Patients who have urogenital symptoms or vaginal dryness at baseline as reported by baseline questionnaires (VAS, VuAS, PROMIS, etc.)