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Functional Changes in the Stomach and Esophagus After One Anastomosis Gastric Bypass- OAGB

Functional Changes in the Stomach and Esophagus After One Anastomosis Gastric Bypass- OAGB

Recruiting
18-65 years
All
Phase N/A
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Overview

Evaluation of the functional changes in the stomach and esophagus of patients undergoing One Anastomosis Gastric Bypass (OAGB)

Eligibility

Inclusion Criteria:

  • BMI> 35 kg/m2
  • 2 years of controlled conservative obesity treatment without weight reduction
  • patients should give their consent to participate in the study

Exclusion Criteria:

  • Less than 2 years of conservative obesity treatment
  • cancer
  • cirrhosis Child-Pough score A
  • Crohn's disease
  • serious psychiatric disorder, which led to in-hospital treatment in psychiatric clinic in the past two years
  • drug consumption
  • non-compliance
  • hiatal hernia > 4cm
  • gastric pouch < 10cm
  • Barett esophagus
  • erosive esophagitis Grade C or D according to the Los Angeles Classification
  • endoscopically proven gastric stricture
  • acid exposition time > 6% (Lyon criteria)
  • reflux episodes> 80 /24 hours (Lyon criteria)
  • insufficient low esophageal sphincter according to manometry findings
  • pathological findings in the impedance pH-metry (acid and non-acid reflux)

Study details
    Obesity
    Morbid
    GERD
    Ulcer
    Gastric

NCT04422405

Spital Limmattal Schlieren

16 June 2025

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