Overview
The ENDOFERT Study is an open, multicenter, randomized, parallel-group, controlled trial. This study includes patients presenting colorectal DIE and infertility. Patients will be randomized in two parallel-groups; one group underwent complete surgery of colorectal DIE prior to ART and the other group underwent ART alone (ratio 1:1)
Eligibility
Inclusion Criteria:
- Primary and secondary infertility
- Indication for IVF
- Persistent pain related to endometriosis with analgesic medical treatment failure
- Persistent pain including at least one of the following digestive symptoms related to endometriosis: Dyschesia / Sub-occlusive syndrome / Rectal bleeding / Painful defecation
- Colorectal deep infiltrating endometriosis : Whatever lesion size / With at least rectal serosal involvement / Confirmed by MRI and 1 different investigation: vaginal ultrasound echography or coloscopic CT scan or rectal endoscope ultrasound
- Eligible for DIE surgery
Exclusion Criteria:
- Contraindication to pregnancy or to IVF
- Viral risk
- Previous IVF cycle(s)
- Previous colorectal surgery
- Need of myomectomy during surgery
- The use of oocytes donor