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Primary Failure of Eruption (PFE) : Highlighting of Clinical, Radiological and Genetic Diagnostic Criteria: Consequences on the Therapeutic Management

Primary Failure of Eruption (PFE) : Highlighting of Clinical, Radiological and Genetic Diagnostic Criteria: Consequences on the Therapeutic Management

Recruiting
6 years and older
All
Phase N/A
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Overview

The primary purpose of the study is to identify clinical, radiological and genetic diagnostic criteria for Primary Failure of Eruption (PFE).

The secondary purposes are to highlight the genotype-phenotype correlations in the PTHR1 and non-PTHR1 forms and analyze the therapeutic failures.

Eligibility

Inclusion criteria:

  • people over 6 years old
  • people with Primary Failure Eruption

Exclusion criteria:

  • children under 6 years old
  • endocrine pathology that may interfere with dental eruption
  • rickets
  • chemotherapy / radiotherapy
  • bisphosphonate treatment

Study details
    Primary Failure of Eruption

NCT03580785

University Hospital, Strasbourg, France

11 August 2025

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