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Clinical and Radiographic Assessment of Nano-Bioactive Glass Combined With I-PRF Scaffold in Vital Pulp Treatments in Mandibular Molars With Closed Apices

Recruiting
14 - 32 years of age
Both
Phase N/A

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Overview

Clinical, Radiographic and pain assessment of Vital pulp treatment in patients suffering from irreversible pulpitis in mature permanent molars. Total pulpotomy is investigated using I-prf only vs I-prf mixed with Nano-bioactive glass.

Eligibility

Inclusion Criteria:

  • Patients suffering from Symptomatic irreversible pulpitis in mature mandibular molars only will be involved.
  • Tooth should give positive response to cold test
  • Haemostasias should be achieved after total pulpotomy
  • The tooth is restorable and free from advanced periodontal disease, cracks and splits.
  • Patients should be free from any systemic disease that may affect normal healing and predictable outcome.
  • Patients who will agree to the consent and will commit to follow-up period.
  • Patients with mature root apices
  • Patients with no internal or external resorption and no periapical lesions
  • Soft tissues around the tooth are normal with no swelling or sinus tract.

Exclusion Criteria:

  • Patients with immature roots.
  • Haemostasias after 10 minutes can not be controlled after total pulpotomy
  • Patients with any systemic disease that may affect normal healing.
  • Patients with periapical lesions or infections.
  • Pregnant females.
  • Patients who could/would not participate in a 6 months follow-up.
  • Patients with fistula or swelling
  • Patients with necrotic pulp.
  • Patients with old age.

Study details

Vital Pulp Treatment in Mature Permanent Teeth With Irreversible Pulpitis

NCT05876520

Cairo University

25 January 2024

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