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Dose-finding Study: Popliteal Sciatic Nerve Block in Patients Undergoing Diabetic Foot Surgery

Dose-finding Study: Popliteal Sciatic Nerve Block in Patients Undergoing Diabetic Foot Surgery

Non Recruiting
19-80 years
All
Phase N/A

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Overview

The purpose of this study was to determine the minimum effective dose of a local anesthetic for proper anesthesia for popliteal sciatic nerve block under ultrasound guidance in patients undergoing surgery for diabetic foot disease.

Description

Unlike general patients, patients with diabetic foot disease often have diabetic neuropathy and thus have increased sensitivity to local anesthetics. Therefore, when performing sciatic nerve block, it is essential to properly adjust the dose to prevent neurotoxicity and delay in recovery due to local anesthetics.

If the appropriate effective dose of local anesthetic for sciatic nerve block is found in patients with diabetic foot through this study, it is expected that it will be a useful basis for establishing a safe anesthetic method in the case of diabetic foot surgery.

Eligibility

Inclusion Criteria:

  • Adult patients who can be operated under popliteal sciatic nerve block among patients undergoing surgery for diabetic foot disease

Exclusion Criteria:

  1. Infection of the popliteal region
  2. Severe coagulation abnormality
  3. Allergic reaction or hypersensitivity to local anesthetics
  4. Neurological abnormalities other than diabetic neuropathy in the lower extremity of the operation site
  5. When it is impossible to evaluate sensory blockage and motor blockage
  6. When the patient refuses

Study details
    Diabetic Foot
    Diabetic Neuropathies

NCT04981067

Seoul National University Hospital

20 August 2025

FAQs

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